Serene by Nature ~ Mood Balancing Cream

Enjoy Extraordinary Equine Excellence.


A topical calming cream that naturally helps your horse consistently be their best during all their seasonal cycles!

Is Your Horse High Strung, Nervous, Cranky, Spooky, or Suffering from PMS (Pissy~Mare~Syndrome)?

Do you wish you had a calm, focused, and happy horse?  Every day, for every ride, and at every event?  Your wishes can come true! Check out our innovative and unparalleled new product:

Serene by Nature’s nutraceutical cream is the FIRST EVER BIO-IDENTICAL endocrine balancing support for equines.

Veterinarian Tested, Approved and Recommended.  Natural, Effective, and Affordable.

**  USEF looking at Medroxy usage… **

This one of a kind metabolic formula was created to intrinsically support equines during their regular seasonal cycles, which may benefit their attitude, performance, focus, and trainability, as well as breeding thru gestation.  For those looking for a holistic alternative to prescription synthetic hormones, or herbal blends that will test negatively (USEF & FEI compliance), Serene by Nature topical cream may be the best possible natural choice.

Supporting the endocrine system is essential to achieving optimal health and over all well-being, as the balance or lack of, directly effects every cell in the body and the brain. A healthy balance is a vital component for overall good health, attitude, performance, and a flourishing and stable reproductive system.

  • FIRST EVER Bio-Identical endocrine balancing support.
  • Veterinarian tested, approved and recommended.
  • May be beneficial for nervous, spooky, hard to handle horses, and mares with PMS.
  • Helps to balance mares throughout all their seasonal cycles, promoting regularity.
  • May be advantageous for breeding and pregnant mares.
  • No known negative side effects or drug interactions.
  • Naturally safe alternative to synthetic drugs.
  • One tube lasts about 3 cycles, or 2-3 months.
  • Unlike most herbal products – won’t test ‘negatively’ on competition horses.
  • Easy topical application, no stress for fussy eaters.

Our Mission…

Horse Rescues We Support…


Disclaimer: Serene by Nature, nor any third party associated with, related to, or linked to their businesses or websites, expressly disclaims any responsibility for, and makes no representations or warranties regarding, any statement, information, materials, or content found on or included in Serene by Nature’s marketing materials/websites, or any third party marketing materials/websites related to, associated with or linked to Serene by Nature’s business or website. Serene by Nature is not intended to diagnose, treat, cure, prevent any disease or replace proper medical care. These statements have not yet been approved by the FDA.